WHAT IS SIBO

WHAT IS SIBO

WHAT IS SIBO

Small Intestinal Bacterial Overgrowth

SIBO (pronounced “see-bo”) is a gastrointestinal (GI) disorder that occurs when there is an overabundance of bacteria in your small intestine. While it’s normal to have bacteria in your small intestine, if it is the wrong kind or too many, it can disrupt the balance of your gut microbiome and wreak havoc on your digestive system. These “disruptor” bacteria cause various health problems including painful bloating, diarrhea, constipation, brain fog, and fatigue.   

SIBO is not a primary disease but rather a condition resulting from an underlying root issue that is causing the dysmotility. Common causes of SIBO include:

  • Other GI diseases, including IBS, IBD, Celiac disease, and others

  • Prescription medications such as antibiotics or opioids

  • Food poisoning

Despite its prevalence, SIBO is frequently overlooked, misdiagnosed, or dismissed. Many people with SIBO struggle for years with symptoms before receiving an accurate diagnosis.

Symptoms of SIBO

SIBO results in many debilitating symptoms in the digestive system and beyond:

Digestive Symptoms:

Digestive Symptoms:

  • Abdominal bloating and distension

  • Abdominal discomfort and/or cramps

  • Excessive gas leading to belching and/or flatulence

  • Heartburn and/or acid reflux

  • Nausea

  • Nutritional deficiencies, including iron and B12

Digestive:

  • Abdominal bloating and distension

  • Abdominal discomfort and/or cramps

  • Excessive gas leading to belching and/or flatulence

  • Heartburn and/or acid reflux

  • Nausea

  • Nutritional deficiencies, including iron and B12

Non-Digestive Symptoms:

Non-Digestive Symptoms:

  • Fatigue

  • Brain Fog

  • Headaches

  • Weight loss/gain

  • Joint pain

  • Mood symptoms

  • Skin problems, such as eczema and rashes

Non-Digestive:

  • Fatigue

  • Brain Fog

  • Headaches

  • Weight loss/gain

  • Joint pain

  • Mood symptoms

  • Skin problems, such as eczema and rashes

SIBO & IMO

SIBO & IMO

SIBO & IMO

Types of SIBO

It can be useful to categorize SIBO by the major gases the overgrowth produces. There are three types: hydrogen dominant (SIBO), methane dominant (IMO) and hydrogen sulfide dominant. Because the gases are produced by different strains of bacteria or archaea that are over colonizing the small intestine, this is the clearest indicator of your type. 

Antibiotic therapy can be tailored to target the specific type of overgrowth if known. Additionally, there are different symptom profiles associated with each type:

  • Hydrogen Dominant SIBO typically causes diarrhea in patients and overlaps with the symptoms of IBS-D.

  • Methane Dominant SIBO has been reclassified as Intestinal Methanogen Overgrowth (IMO), as the methane producing microorganisms are archaea not bacteria. These methanogens are naturally present in the gut, but can overgrow in both the small intestine and the large intestine. IMO typically causes constipation and overlaps with the symptoms of IBS-C.

  • Hydrogen Sulfide Dominant SIBO typically causes diarrhea in patients, similar to hydrogen dominant SIBO. Certain breath tests measure hydrogen sulfide levels alongside hydrogen and methane and can help differentiate between the types when symptoms overlap.

SIBO Awareness

April 8th is SIBO Awareness Day

This April, join the movement to raise awareness for SIBO—an often-overlooked condition affecting millions. Our mission is to educate, support, and provide resources so those suffering can find the right treatment, take control of their gut health, and reclaim their lives.

38%

of IBS patients have SIBO

4%

in US suffer from digestive discomfort

35%

in US have never heard of SIBO

0%
in US feel dismissed by doctors when discussing GI symptoms

SIBO Awareness

April 8th is SIBO Awareness Day

This April, join the movement to raise awareness for SIBO—an often-overlooked condition affecting millions. Our mission is to educate, support, and provide resources so those suffering can find the right treatment, take control of their gut health, and reclaim their lives.

38%

of IBS patients have SIBO

4%

in US suffer from digestive discomfort

35%

in US have never heard of SIBO

0%
of people feel dismissed by doctors when discussing GI symptoms

SIBO Awareness

April 8th is SIBO Awareness Day

This April, join the movement to raise awareness for SIBO—an often-overlooked condition affecting millions. Our mission is to educate, support, and provide resources so those suffering can find the right treatment, take control of their gut health, and reclaim their lives.

38%

of IBS patients have SIBO

4%

in US suffer from digestive discomfort

35%

in US have never heard of SIBO

0%
of people feel dismissed by doctors when discussing GI symptoms

SIBO Diagnosis

Official diagnosis of of SIBO can help guide effective treatment and improve digestive health. Consult with your doctor to determine the best method for you.

Which test is right for you?

Which test is right for you?

Which test is right for you?

Breath testing icon
Breath Test

Most widely available and least invasive. Options now include at-home testing kits as well as in-clinic testing

Breath testing icon
Breath Test

Most widely available and least invasive. Options now include at-home testing kits as well as in-clinic testing

Breath testing icon
Breath Test

Most widely available and least invasive. Options now include at-home testing kits as well as in-clinic testing

Bowel aspiration icon
Bowel aspiration

More costly and invasive procedure that provides a more in-depth view of the bacteria

Bowel aspiration icon
Bowel aspiration

More costly and invasive procedure that provides a more in-depth view of the bacteria

Bowel aspiration icon
Bowel aspiration

More costly and invasive procedure that provides a more in-depth view of the bacteria

Symptomatic diagnosis icon
Symptomatic Diagnosis

Doctors can review your symptoms and make a diagnosis based on your clinical presentation

Symptomatic diagnosis icon
Symptomatic Diagnosis

Doctors can review your symptoms and make a diagnosis based on your clinical presentation

Symptomatic diagnosis icon
Symptomatic Diagnosis

Doctors can review your symptoms and make a diagnosis based on your clinical presentation

#KnowSIBO

#KnowSIBO

#KnowSIBO

Know SIBO: Frequently Asked Questions

What is SIBO (Small Intestinal Bacterial Overgrowth)?

An overgrowth of bacteria in the small intestine. These ‘disruptor’ bacteria create excessive gas and lead to a multitude of uncomfortable symptoms.

What are the common symptoms of SIBO?

Bloating is the most common symptom for SIBO patients, as the bacterial overgrowth produces gas that can get trapped in the small intestine. Other symptoms include weight changes, flatulence, diarrhea, constipation, brain fog and fatigue.

How does SIBO differ from IBS (Irritable Bowel Syndrome)?

SIBO is a subgroup of IBS characterized by bacterial overgrowth in the small intestine. Recent studies have found that up to 78% of IBS patients- as many as 30 million Americans- have SIBO.

Are there different kinds of SIBO?

It can be useful to categorize SIBO by the major gases the overgrowth produces. This gives valuable insight into the strains of bacteria or archaea that are colonizing the small intestine. Antibiotic therapy can be tailored to target the specific strains if known. Additionally, there are different symptom profiles associated with each type. For example, methane dominant SIBO, or IMO, tends to cause constipation.

What are the five top terms to know to understand SIBO?

The gut microbiome refers to the microbes in the gut. This includes bacteria, fungi, viruses, and archaea (single cell organisms similar to bacteria). Gut motility refers to the coordinated movement of the gut to move food through the digestive system. SIBO remission refers to the end goal of treatment to achieve relief from symptoms allowing you to return to a normal lifestyle.

What causes SIBO to develop?

SIBO is not a standalone condition but rather a secondary disorder arising from other underlying diseases, structural abnormalities in the digestive system, or external triggers. Anything that disrupts gut motility, impairs digestion, or weakens the body’s ability to regulate bacteria can contribute to SIBO. Some of the most common factors known to cause SIBO can be found on our Root Causes page.

Is SIBO contagious?

No, SIBO is not contagious, however some of the underlying conditions, for example norovirus food poisoning, may be considered contagious.

How common is SIBO?

Estimates vary but one retrospective study found that 33.8% of patients that underwent breath testing after reporting gastrointestinal distress had SIBO.

What is SIBO (Small Intestinal Bacterial Overgrowth)?

An overgrowth of bacteria in the small intestine. These ‘disruptor’ bacteria create excessive gas and lead to a multitude of uncomfortable symptoms.

What are the common symptoms of SIBO?

Bloating is the most common symptom for SIBO patients, as the bacterial overgrowth produces gas that can get trapped in the small intestine. Other symptoms include weight changes, flatulence, diarrhea, constipation, brain fog and fatigue.

How does SIBO differ from IBS (Irritable Bowel Syndrome)?

SIBO is a subgroup of IBS characterized by bacterial overgrowth in the small intestine. Recent studies have found that up to 78% of IBS patients- as many as 30 million Americans- have SIBO.

Are there different kinds of SIBO?

It can be useful to categorize SIBO by the major gases the overgrowth produces. This gives valuable insight into the strains of bacteria or archaea that are colonizing the small intestine. Antibiotic therapy can be tailored to target the specific strains if known. Additionally, there are different symptom profiles associated with each type. For example, methane dominant SIBO, or IMO, tends to cause constipation.

What are the five top terms to know to understand SIBO?

The gut microbiome refers to the microbes in the gut. This includes bacteria, fungi, viruses, and archaea (single cell organisms similar to bacteria). Gut motility refers to the coordinated movement of the gut to move food through the digestive system. SIBO remission refers to the end goal of treatment to achieve relief from symptoms allowing you to return to a normal lifestyle.

What causes SIBO to develop?

SIBO is not a standalone condition but rather a secondary disorder arising from other underlying diseases, structural abnormalities in the digestive system, or external triggers. Anything that disrupts gut motility, impairs digestion, or weakens the body’s ability to regulate bacteria can contribute to SIBO. Some of the most common factors known to cause SIBO can be found on our Root Causes page.

Is SIBO contagious?

No, SIBO is not contagious, however some of the underlying conditions, for example norovirus food poisoning, may be considered contagious.

How common is SIBO?

Estimates vary but one retrospective study found that 33.8% of patients that underwent breath testing after reporting gastrointestinal distress had SIBO.

What is SIBO (Small Intestinal Bacterial Overgrowth)?

An overgrowth of bacteria in the small intestine. These ‘disruptor’ bacteria create excessive gas and lead to a multitude of uncomfortable symptoms.

What are the common symptoms of SIBO?

Bloating is the most common symptom for SIBO patients, as the bacterial overgrowth produces gas that can get trapped in the small intestine. Other symptoms include weight changes, flatulence, diarrhea, constipation, brain fog and fatigue.

How does SIBO differ from IBS (Irritable Bowel Syndrome)?

SIBO is a subgroup of IBS characterized by bacterial overgrowth in the small intestine. Recent studies have found that up to 78% of IBS patients- as many as 30 million Americans- have SIBO.

Are there different kinds of SIBO?

It can be useful to categorize SIBO by the major gases the overgrowth produces. This gives valuable insight into the strains of bacteria or archaea that are colonizing the small intestine. Antibiotic therapy can be tailored to target the specific strains if known. Additionally, there are different symptom profiles associated with each type. For example, methane dominant SIBO, or IMO, tends to cause constipation.

What are the five top terms to know to understand SIBO?

The gut microbiome refers to the microbes in the gut. This includes bacteria, fungi, viruses, and archaea (single cell organisms similar to bacteria). Gut motility refers to the coordinated movement of the gut to move food through the digestive system. SIBO remission refers to the end goal of treatment to achieve relief from symptoms allowing you to return to a normal lifestyle.

What causes SIBO to develop?

SIBO is not a standalone condition but rather a secondary disorder arising from other underlying diseases, structural abnormalities in the digestive system, or external triggers. Anything that disrupts gut motility, impairs digestion, or weakens the body’s ability to regulate bacteria can contribute to SIBO. Some of the most common factors known to cause SIBO can be found on our Root Causes page.

Is SIBO contagious?

No, SIBO is not contagious, however some of the underlying conditions, for example norovirus food poisoning, may be considered contagious.

How common is SIBO?

Estimates vary but one retrospective study found that 33.8% of patients that underwent breath testing after reporting gastrointestinal distress had SIBO.
Logo

Small Intestinal Bacterial Overgrowth (SIBO) affects 1 in 9 people. By providing science-backed resources, research and solutions we support patients on their journey to health.

Learn More

hello@siboawareness.org

This information is in no way intended to replace the guidance of your doctor. SIBOawareness.org does not provide medical advice, diagnosis or treatment.

Newsletter

Join our mailing list: Be the first to hear about new research, receive discounts from our supporters and learn more about managing your SIBO!

© 2025 Gut Microbiome Foundation.

All Rights Reserved

Logo

Small Intestinal Bacterial Overgrowth (SIBO) affects 1 in 9 people. By providing science-backed resources, research and solutions we support patients on their journey to health.

Learn More

hello@siboawareness.org

This information is in no way intended to replace the guidance of your doctor. SIBOawareness.org does not provide medical advice, diagnosis or treatment.

Newsletter

Join our mailing list: Be the first to hear about new research, receive discounts from our supporters and learn more about managing your SIBO!

© 2025 Gut Microbiome Foundation. All Rights Reserved

Logo

Small Intestinal Bacterial Overgrowth (SIBO) affects 1 in 9 people. By providing science-backed resources, research and solutions we support patients on their journey to health.

Learn More

hello@siboawareness.org

This information is in no way intended to replace the guidance of your doctor. SIBOawareness.org does not provide medical advice, diagnosis or treatment.

Newsletter

Join our mailing list: Be the first to hear about new research, receive discounts from our supporters and learn more about managing your SIBO!

© 2025 Gut Microbiome Foundation.
All Rights Reserved