Corn syrup poured into spoon
Corn syrup poured into spoon
Corn syrup poured into spoon

High-fructose corn syrup (HFCS) is a sweetener commonly used in processed foods and drinks. It's made from corn starch and considered a cheaper alternative to sugar. However, HFCS may have several negative health effects, especially if you have Small Intestinal Bacterial Overgrowth (SIBO).

High fructose corn syrup
High fructose corn syrup
High fructose corn syrup

Here's why HFCS doesn’t belong in your diet if you want to protect your gut health:

  1. Fructose overload: Fructose is a sugar that is commonly found in fruits and is generally considered to be a healthy source of sugar. But unlike other sugars, it’s metabolized primarily in the liver. Too much of it can overload your system and increase the risks for fatty liver disease, insulin resistance, and type 2 diabetes.

  2. Gut destabilizer: Studies have discovered that HFCS may alter the composition of the gut microbiome, which is the collection of microbes living in the digestive tract. Imbalances in the gut microbiome have been linked to several health issues, including inflammatory bowel disease (IBD) and obesity.

  3. General health hazard: High levels of HFCS can raise triglyceride levels in your blood, increasing your risk for heart disease. There is also some research suggesting that it could negatively impact your brain health, impairing memory and learning, and even contributing to a higher risk of developing Alzheimer’s disease.

While it is still a relatively new area of research, it is clear that consuming high amounts of HFCS is tough on the gut, heart, and brain. It’s a good idea to limit your intake of processed foods and beverages that contain HFCS. Instead, opt for healthier sources of sugar, such as whole fruits and natural sweeteners.

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Small Intestinal Bacterial Overgrowth (SIBO) affects 1 in 9 people. By providing science-backed resources, research and solutions we support patients on their journey to health.

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hello@siboawareness.org

This information is in no way intended to replace the guidance of your doctor. SIBOawareness.org does not provide medical advice, diagnosis or treatment.

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© 2025 Gut Microbiome Foundation.

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Logo

Small Intestinal Bacterial Overgrowth (SIBO) affects 1 in 9 people. By providing science-backed resources, research and solutions we support patients on their journey to health.

Learn More

hello@siboawareness.org

This information is in no way intended to replace the guidance of your doctor. SIBOawareness.org does not provide medical advice, diagnosis or treatment.

Newsletter

Join our mailing list: Be the first to hear about new research, receive discounts from our supporters and learn more about managing your SIBO!

© 2025 Gut Microbiome Foundation. All Rights Reserved

Logo

Small Intestinal Bacterial Overgrowth (SIBO) affects 1 in 9 people. By providing science-backed resources, research and solutions we support patients on their journey to health.

Learn More

hello@siboawareness.org

This information is in no way intended to replace the guidance of your doctor. SIBOawareness.org does not provide medical advice, diagnosis or treatment.

Newsletter

Join our mailing list: Be the first to hear about new research, receive discounts from our supporters and learn more about managing your SIBO!

© 2025 Gut Microbiome Foundation.
All Rights Reserved